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Richard C Hubbard Selected Research

parecoxib

10/2004A clinical trial demonstrates the analgesic activity of intravenous parecoxib sodium compared with ketorolac or morphine after gynecologic surgery with laparotomy.
8/2004Parecoxib sodium demonstrates gastrointestinal safety comparable to placebo in healthy subjects.
5/2004Analgesic efficacy of preoperative parecoxib sodium in an orthopedic pain model.
9/2003Single doses of parecoxib sodium intravenously are as effective as ketorolac in reducing pain after oral surgery.
6/2003Efficacy and safety of the cyclooxygenase 2 inhibitors parecoxib and valdecoxib in patients undergoing coronary artery bypass surgery.
4/2003Parecoxib sodium, a parenteral cyclooxygenase 2 selective inhibitor, improves morphine analgesia and is opioid-sparing following total hip arthroplasty.
8/2002Efficacy and safety of intravenous parecoxib sodium in relieving acute postoperative pain following gynecologic laparotomy surgery.
6/2002Intravenous parecoxib sodium foracute pain after orthopedic knee surgery.
1/2002Upper GI mucosal effects of parecoxib sodium in healthy elderly subjects.

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Richard C Hubbard Research Topics

Disease

7Pain (Aches)
10/2004 - 06/2002
5Postoperative Pain
10/2004 - 06/2002
2Ulcer
08/2004 - 01/2002
2Peptic Ulcer (Peptic Ulcers)
08/2004 - 01/2002
1Wound Infection (Wound Infections)
06/2003
1Fever (Fevers)
04/2003
1Vomiting
04/2003
1Duodenal Ulcer (Curling's Ulcer)
01/2002
1Stomach Ulcer (Gastric Ulcer)
01/2002

Drug/Important Bio-Agent (IBA)

9parecoxibIBA
10/2004 - 01/2002
6KetorolacIBA
10/2004 - 01/2002
5Analgesics (Analgesic Drugs)IBA
10/2004 - 06/2002
4Morphine (MS Contin)FDA LinkGeneric
10/2004 - 06/2002
1ProdrugsIBA
05/2004
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
05/2004
1valdecoxib (Bextra)FDA Link
06/2003
1Opioid Analgesics (Opioids)IBA
04/2003

Therapy/Procedure

2Analgesia
10/2004 - 08/2002
2Laparotomy
10/2004 - 08/2002
1Intravenous Administration
05/2004
1Oral Surgery (Maxillofacial Surgery)
09/2003
1Hysterectomy
08/2002
1Uterine Myomectomy
08/2002